Effect of regularity of exposure to chronic immobilization stress on the circadian pattern of pituitary adrenal hormones, growth hormone, and thyroid stimulating hormone in the adult male rat

doi:10.1016/0306-4530(93)90056-Q

Psychoneuroendocrinology

Volume 18, Issue 1, 1993, Pages 67-77

https://doi.org/10.1016/0306-4530(93)90056-Q Get rights and content

Abstract

Circadian variation of serum levels of adrenocorticotropin hormone (ACTH), corticosterone, growth hormone (GH), and thyroid-stimulating hormone (TSH) were studied in three groups of adult male rats exposed to chronic intermittent immobilization stress (IMO) for 2 hr daily under different schedules. IMO resulted in reduced food intake, body weight loss, and increased adrenal weight. ACTH levels were not affected but corticosterone levels were increased in all IMO rats as compared to control ones during the diurnal phase of the circadian cycle. IMO decreased serum GH and TSH levels but the circadian pattern of secretion was influenced in a complex way depending on the specific pattern of daily exposure to IMO. Differences observed between the IMO groups were not caused by differences in food intake because its circadian rhythm was very similar in all IMO groups. These results suggest that regularity of exposure to immobilization alters in a complex fashion circadian GH and TSH rhythms.

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ArticleEffect of regularity of exposure to chronic immobilization stress on the circadian pattern of pituitary adrenal hormones, growth hormone, and thyroid stimulating hormone in the adult male rat

Abstract

Physiol Behav

Life Sci

Biol Psychiatr

Physiol Behav

Psychoneuroendocrinology

Brain Res

Pharmacol Biochem Behav

Predictable and unpredictable shock: Behavioral measures of aversion and physiological measures of stress

Psychol Bull

Chronic stress increases serotonin and noradrenaline in rat brain and sensitizes their responses to a further acute stress

J Neurochem

Corticotropin-releasing hormone (CRH) directly stimulates corticosterone secretion by the rat adrenal gland

Endocrinology

Contribution of neurochemical change to stress-induced behavioral deficits

Chronic stress reduced GH response to the serotonin agonist 5-methoxy N,N-dimethyltriptamine but did not alter pituitary-adrenal, prolactin, or TSH responses in the rat

Stress Med

A simple procedure for direct corticosterone radioimmunoassay in the rat

Rev Esp Fisiol

Evidence that the pituitary-adrenal axis does not cross-adapt to stressors: Comparison to other physiological variables

Neuroendocrinology

Effect of chronic crowding and cold on the pituitary-adrenal system: Responsiveness to an acute stimulus during chronic stress

Pharmacology

Interaction between chronic stress and clomipramine treatment in rats

Ultradian rhythm of growth hormone secretion and sleep in the adult male rat

J Physiol

Comparison of synchronization of circadian corticosteroid rhythms by photoperiod and food

Article
Effect of regularity of exposure to chronic immobilization stress on the circadian pattern of pituitary adrenal hormones, growth hormone, and thyroid stimulating hormone in the adult male rat