Psychoneuroendocrinology
Volume 34, Issue 3 , Pages 299-306 , April 2009

The cortisol awakening response, seasonality, stress and arousal: A study of trait and state influences

  • Lisa Thorn

      Affiliations

    • Department of Psychology, University of Westminster, 309 Regent Street, London W1B 2UW, UK
  • ,
  • Frank Hucklebridge

      Affiliations

    • Department of Human and Health Sciences, University of Westminster, 115 New Cavendish Street, London W1W 6UW, UK
  • ,
  • Phil Evans

      Affiliations

    • Department of Psychology, University of Westminster, 309 Regent Street, London W1B 2UW, UK
  • ,
  • Angela Clow

      Affiliations

    • Department of Psychology, University of Westminster, 309 Regent Street, London W1B 2UW, UK
    • Corresponding Author InformationCorresponding author. Tel.: +44 207 911 5000; fax: +44 207 911 5106.

Received 4 June 2008 ,Revised 18 November 2008 ,Accepted 20 November 2008.

References 

  1. De Weerth C, Buitelaar JK. Cortisol awakening response in pregnant women. Psychoneuroendocrinology. 2005;30:902–907
  2. Edwards S, Clow A, Evans P, Hucklebridge F. Exploration of the awakening cortisol response in relation to diurnal cortisol secretory activity. Life Sci. 2001;68:2093–2103
  3. Golden RN, Gaynes BN, Ekstrom RD, Hamer RM, Jacobsen FM, Suppes T, et al. The efficacy of light therapy in the treatment of mood disorders: a review and meta-analysis of the evidence. Am. J. Psychiatry. 2005;162:656–662
  4. Hardin TA, Wehr TA, Brewerton T, Kasper S, Berrettini W, Rabkin J, et al. Evaluation of seasonality in 6 clinical populations and 2 normal populations. J. Psychiatr. Res. 1991;25:75–87
  5. Hegde AL, Woodson H. Prevalence of seasonal changes in mood and behavior during the winter months in central Texas. Psychiatry Res. 1996;62:265–271
  6. Hellhammer J, Fries E, Schweisthal OW, Schlotz W, Stone AA, Hagemann D. Several daily measurements are necessary to reliably assess the cortisol rise after awakening: state and trait components. Psychoneuroendocrinology. 2007;32:80–86
  7. Hewig J, Schlotz W, Gerhards F, Breitenstein C, Lurken A, Naumann E. Associations of the cortisol awakening response (CAR) with cortical activation asymmetry during the course of an exam stress period. Psychoneuroendocrinology. 2008;33:83–91
  8. Kudielka BM, Kern S. Cortisol day profiles in victims of mobbing (bullying at the work place): preliminary results of a first psychobiological field study. J. Psychosom. Res. 2004;56:149–150
  9. Kunz-Ebrecht SR, Kirschbaum C, Marmot M, Steptoe A. Differences in cortisol awakening response on work days and weekends in women and men from the Whitehall II cohort. Psychoneuroendocrinology. 2004;29:516–528
  10. Kupper N, de Geus EJC, van den Berg M, Kirschbaum C, Boomsma DI, Willemsen G. Familial influences on basal salivary cortisol in an adult population. Psychoneuroendocrinology. 2005;30:857–868
  11. Leproult R, Colecchia EF, L’Hermite-Baleriaux M, Van Cauter E. Transition from dim to bright light in the morning induces an immediate elevation of cortisol levels. J. Clin. Endocrinol. Metab. 2001;86:151–157
  12. Mackay C, Cox T, Burrows G, Lazzerini T. An inventory for the measurement of self-reported stress and arousal. Br. J. Soc. Clin. Psychol. 1978;17:283–284
  13. Okawa M, Shirakawa S, Uchiyama M, Oguri M, Kohsaka M, Mishima K, et al. Seasonal variation of mood and behaviour in a healthy middle-aged population in Japan. Acta Psychiatr. Scand. 1996;94:211–216
  14. Pruessner JC, Wolf OT, Hellhammer DH, Buske-Kirschbaum A, von Auer K, Jobst S, et al. Free cortisol levels after awakening: a reliable biological marker for the assessment of adrenocortical activity. Life Sci. 1997;61:2539–2549
  15. Reid S, Towell AD, Golding JF. Seasonality, social zeitgebers and mood variability in entrainment of mood—implications for seasonal affective disorder. J. Affect Disord. 2000;59:47–54
  16. Rosen LN, Rosenthal NE. Seasonal variations in mood and behavior in the general population—a factor analytic approach. Psychiatry Res. 1991;38:271–283
  17. Rosenthal NE, Genhart M, Sack DA, Skwerer RG, Wehr TA. Seasonal affective disorder and its relevance for the understanding and treatment of bulimia. In:  Hudson JI,  Pope HG editor. The Psychobiology of Bulimia. Washington, DC: American Psychiatric Press; 1987;p. 203–228
  18. Rosmalen JGM, Oldehinkel AJ, Ormel J, de Winter AF, Buitelaar JK, Verhulst FC. Determinants of salivary cortisol levels in 10–12 year old children: a population-based study of individual differences. Psychoneuroendocrinology. 2005;30:483–495
  19. Scheer F, Buijs RM. Light affects morning salivary cortisol in humans. J. Clin. Endocrinol. Metab. 1999;84:3395–3398
  20. Schlotz W, Hellhammer J, Schulz P, Stone AA. Perceived work overload and chronic worrying predict weekend–weekday differences in the cortisol awakening response. Psychosom. Med. 2004;66:207–214
  21. Sher L. Etiology, pathogenesis, and treatment of seasonal and non-seasonal mood disorders: possible role of circadian rhythm abnormalities related to developmental alcohol exposure. Med. Hypotheses. 2004;62:797–801
  22. Thorn L, Hucklebridge F, Esgate A, Evans P, Clow A. The effect of dawn simulation on the cortisol response to awakening in healthy participants. Psychoneuroendocrinology. 2004;29:925–930
  23. Thorn L, Hucklebridge F, Evans P, Clow A. Suspected non-adherence and weekend versus week day differences in the awakening cortisol response. Psychoneuroendocrinology. 2006;31:1009–1018
  24. Wuest S, Federenko IS, Hellhammer DH, Kirschbaum C. Genetic factors, perceived chronic stress, and the free cortisol response to awakening. Psychoneuroendocrinology. 2000;25:707–720
  25. Wuest S, Wolf J, Hellhammer DH, Federenko IS, Schommer N, Kirschbaum C. The cortisol response to awakening—normal values and confounds. Noise Health. 2000;7:77–85

PII: S0306-4530(08)00316-8

doi: 10.1016/j.psyneuen.2008.11.005

Psychoneuroendocrinology
Volume 34, Issue 3 , Pages 299-306 , April 2009